Search results for "Hippocampal segmentation"

showing 2 items of 2 documents

Reference standard space hippocampus labels according to the European Alzheimer's Disease Consortium–Alzheimer's Disease Neuroimaging Initiative harm…

2017

Abstract Introduction A harmonized protocol (HarP) for manual hippocampal segmentation on magnetic resonance imaging (MRI) has recently been developed by an international European Alzheimer's Disease Consortium–Alzheimer's Disease Neuroimaging Initiative project. We aimed at providing consensual certified HarP hippocampal labels in Montreal Neurological Institute (MNI) standard space to serve as reference in automated image analyses. Methods Manual HarP tracings on the high-resolution MNI152 standard space template of four expert certified HarP tracers were combined to obtain consensual bilateral hippocampus labels. Utility and validity of these reference labels is demonstrated in a simple …

Magnetic Resonance Imaging/methods/standardsMaleJaccard indexEpidemiologyComputer sciencemethods [Pattern Recognition Automated]Image ProcessingAutomated/methods/standardsHippocampusPattern Recognition Automatedddc:616.89methods [Magnetic Resonance Imaging]0302 clinical medicinemethods [Image Processing Computer-Assisted]Image Processing Computer-AssistedComputer-Assisted/methods/standardsHARPdiagnostic imaging [Hippocampus]Health Policy05 social sciencesOrgan SizeReference StandardsMagnetic Resonance ImagingHippocampal segmentationstandards [Image Processing Computer-Assisted]Psychiatry and Mental healthNeuroimaging/methods/standardsFemalemethods [Neuroimaging]Hippocampus/diagnostic imagingAlzheimer's Disease Neuroimaging InitiativeAlzheimer Disease/diagnostic imagingNeuroimagingPattern Recognition050105 experimental psychology03 medical and health sciencesCellular and Molecular NeuroscienceDevelopmental NeuroscienceNeuroimagingAlzheimer DiseaseHumans0501 psychology and cognitive sciencesddc:610Reference standardsAgedProtocol (science)standards [Magnetic Resonance Imaging]business.industryPattern recognitionGold standard (test)Neurology (clinical)Artificial intelligenceGeriatrics and Gerontologybusinessdiagnostic imaging [Alzheimer Disease]standards [Pattern Recognition Automated]Neurosciencestandards [Neuroimaging]030217 neurology & neurosurgeryAlzheimer's & Dementia
researchProduct

Manual segmentation qualification platform for the EADC-ADNI harmonized protocol for hippocampal segmentation project

2015

The use of hippocampal volumetry as a biomarker for Alzheimer's disease (AD) requires that tracers from different laboratories comply with the same segmentation method. Here we present a platform for training and qualifying new tracers to perform the manual segmentation of the hippocampus on magnetic resonance images (MRI) following the European Alzheimer's Disease Consortium and Alzheimer's Disease Neuroimaging Initiative (EADC-ADNI) Harmonized Protocol (HarP). Our objective was to demonstrate that the training process embedded in the platform leads to increased compliance and qualification with the HarP.Thirteen new tracers' segmentations were compared with benchmark images with respect t…

Pathologymedicine.medical_specialtyInservice TrainingJaccard indexEpidemiologyComputer scienceHippocampusCellular and Molecular Neuroscienceddc:616.89Imaging Three-DimensionalDevelopmental NeuroscienceNeuroimagingAlzheimer DiseaseImage Processing Computer-AssistedmedicineHumansCognitive DysfunctionSegmentationStatistical hypothesis testingHARPProtocol (science)business.industryHealth PolicyReproducibility of ResultsPattern recognitionOrgan SizeMagnetic Resonance ImagingHippocampal segmentationPsychiatry and Mental healthManual segmentationNeurology (clinical)Artificial intelligenceGeriatrics and Gerontologybusiness
researchProduct